CONTENTS №10-2014

3          Bacherikov G.A. Shchelkovo biocombinat – 90 years 

In 2014 90 years from the date of FKP “Shelkovo Biocombine” basis are executed. Biocombine – one of leading enterprises of the Russian Federation on which make more than 30 types of production. Introduction of the GMP standards on all sites of production of medicines – their quality guarantee. Participates in the Federal target program in the field of ensuring cheminal and biological safety-2020. Key words: anniversary, 90 years, production, production, quality.

PRACTIC: EXPERIMENT, PROBLEMS, PERSPECTIVES

7          Donnik I.M., Shkuratova I.A., Tatarchuk A.T., Lisov A.V., Petropavlovskiy M.V., Mikheev M.P., Krasnopyorov V.A. The effective system of measures against bovine leukemia in the Middle Urals

In the Urals region were conducted a complex program of antileukemic activities, which resulted was elimination of almost all troubled by leukemia herds, healthy cattle (150 thousand heads) in the public and the individual sector. Key words: virus bovine leukemia, hematologic studies, serology, Ural system, improving antileukemic activities, epizootic process.

12        Schepetkina S.V.  Economic efficiency diagnostic, preventive and therapeutic measures on the example of mastitis in cows

Article is devoted to search of ways of calculation of economic efficiency of diagnostic, preventive, medical actions from the point of view of the veterinarian on the example of mastitis at cows. Key words: cattle, mastitis, economic efficiency, diagnostic, medical, preventive actions.

INFECTIOUS  DISEASES

15        Raev S.A., Aliper T.I. Diagnosis and prevention enzootic pneumonia pigs

This article is about general characteristics of the enzootic pneumonia, its economic importance. Diagnosis is based on different assays. Vaccination is one of the most important strategies to control EP. Immunization by currently available inactivated vaccines improves production performance, but it cannot prevent colonization of M.hyo. Key words: enzootic pneumonia, Mycoplasma hyopneumoniae, diagnosis, vaccination, production performance, efficacy.

21        Lelyak A.A., Lelyak A.I., Revkov N.V., Tareeva I.A. The analysis of otitis externa etiology in pets

The given article contains the data on a range of the agents causing Otitis Externa. The data was obtained from the clinical trials in cats and dogs. The article also presents the findings of the investigations into susceptibility of the isolated microbial strains to the most common and used antibiotics at present. It has been found that among microbes which areagents causing external otitises in small domestic animals, aerobic bacteria of the family Enterobacteriaceae, genus Staphylococcus are often observed, and bacteria of genus Pseudomonas are to a lesser extent. Escherichia coli and Enterobacter cloacae have appeared etiologically significant among the enteric bacteria. Staphylococcus aureus has been found more often than other representatives of the coccal microflora. In studying the susceptibility of the isolated cultures to antimicrobial drugs it was determined that the isolated cultures are resistant to β-lactam antibiotics, susceptibility of every pathogen to the cephalosporins and fluoroquinolones being preserved. Key words: otitis externa, antibiotics, antibiotic resistance.

24        Volkova M.A., Irza A.V., Lazareva S.P., Bahchin I.V., Chvala I.A., Drygin V.V.  Research of biological properties of avian adenovirus isolate FAdV2/1/2012

Avian adenovirus was isolated from the liver of 18-days old chickens from the farm in Belgorodskaya Oblast. In 2012, virus was isolated on the culture of LMH-cells with the signs of cytopathic effect, and identified using RT-PCR method followed by the sequencing of the hexon gene fragment as avian adenovirus type D. Using experimental oral infection process on 7-days old broiler type chickens we witnessed the development of inclusion body hepatitis. Key words: avian adenovirus, hepatitis with inclusion bodies.

29        Abdulloev Kh.S., Dandal A.Sh., Frolov S.V., Kulakov V.Yu. Day old vaccination against infectious bronchitis virus

We used commercial chickens having passive immunity to the infectious bronchitis virus, some of them were vaccinated against IBV at the age of 1 day. After 7 days the chickens were challenged. It was found that, serum antibody titers in chickens of both groups had no significant difference at the challenge moment. However, vaccinated chickens were more resistant to challenge. Average vaccination efficiency at 5 – 14 days after challenge was 66,34 %. Key words: avian infectious bronchitis, vaccination, passive immunity.            

INVASIVE DISEASES

32        BittirovA.M., KalabekovA.А., KuznetsovV.M., ShipshevB.M., KabardievS.sh.AtaevA.M., MidovaL.A., BittirovaA.A. Ekto- and endoparasites ruminants animals in the plains area regions of Northern Caucasus

In the plains of Kabardino-Balkaria fauna complex parasites of cattle and small livestock animals is, respectively, 287 and 325 species of ekto- and endoparasites. The most frequently in cattle and sheep of different age populations occur association fasciolae, dicrocoelium, teniid, intestinal strongyles (bunostomum, nematodirus, trihostrongilyus, gemonhus, hаbertia) moniezia, eimeria, iodides and midges. Key words: North Caucasus, flat area, sheep, cattle, type, worms, extensiveness and intensity invasion.  

34        AndreevaY.N. A modern approach to overcome the increasing resistance of coccidian

The actualization of the problem of increasing resistance of coccidia in the conditions of modern industrial poultry. Combined anticoccidial drugs as a means to overcome resistance of coccidia and for improve the performance of broilers. Key words: coccidiosis, broilers, combined coccidiostats, rotation programs.  

OBSTETRICS, GYNECOLOGY

37        NezhdanovA.G., SmirnovaY.V.The increase of cow resistance to postpartum diseases with the use of Selemag and Immunofan 

The efficiency of antioxidative and immunomodulatory drugs application for postpartum uterus and mammary gland diseases, dysfunctional disorders of sexual glands in cows and diarrheal syndrome in neonatal calves in connection with their etiological peculiarities are considered in the article. It is stated that evident response activity to pharmacological drug administration from the side of homeostatic and reproductive organism systems is typical for animals of active behavioral type. Key words: cows, behavior and reproduction, prophylaxis, Selemag, Immunofan.  

40        PudovkinD. N. Prevention of mastitis in cows during the dry period

Etiological factors causing mastitis are microorganisms which penetrate from the environment or by the contact. Mastitis prevention in the dry period is the main factor for the mammary health. Using of Orbenin EDC and OrbeSeal on the first day of the dry period keeps the bovine mammary from being infected. Keywords: mastitis, cows, dry period, Orbenin EDC, OrbeSeal.                                                                                                                                                               PHARMACOLOGY AND TOXICOLOGY

43       Deeva A.V., Sanin A.V., Narovlyansky A.N., Pronin A.V., Ravilov M.N.,  Belousova R.V., Kabanov V.D., Gulukin M.I. Results of  natural biostimulator

Gamavit using for enhancing of reproductive ability, rate of growth and feeding productivity of pigs Gamavit – natural biostimulator with broad clinical capabilities through an integrated and complex composition and several possible mechanisms of action works not only as an immunomodulator, but also as a biogenic stimulator, optimizes metabolism (stimulates growth, increases weight gain), is an adaptogen (increases resistance to stress), blood activator (stimulates erythropoiesis, normalizes blood count), antioxidant, detoxifier, stimulates reproduction. Key words: Gamavit, pig-breeding, fertility, prolificacy, the gross gain, safety, intoxication.  

VETERINARY-SANITARY CONTROL

49        SkvortsovaF.K., AndreyanovO.N.Fermental activity pepsin under diagnostic study on trichinosis  

At meat research on trichinosis by a classical technique of digestion for preparation of artificial gastric juice it is necessary to use proteolytic preparations of firms of Aсros, the Sigma intended for biochemistry. At automated peptolize for allocation of larvae trichinella also it is necessary to use pepsins of firms of Aсros, Sigma and Merck. Russian рepsin of production of firms Shako possesses lower proteolytic activity. Key words: artificial gastric juice, larvae, muscular tissue, peptolize, triсhinellosсopiya.  

52        BachinskayaV.M., DeltsovA.A.Studying the organoleptic indicators and biological value of meat of rabbits receiving preparation Bio-iron with microelements  

In article veterinary and sanitary requirements and meat control when using in a diet of rabbits of a preparation bio - iron with microelements are shined. Studying of organoleptic indicators is carried out and meat value is determined. Harmlessness of application of a preparation bio-iron with microelements on veterinary and sanitary quality of meat is proved. Keywords: rabbit breeding, rabbits, microelements, iron, veterinary and sanitary examination.    

LABORATORY PRACTICE

55      Galnbek T.V., Shulyak A.F., Velichko G.N., Zhuravleva E.A.,  Mnikova L.A., Ishkova T.A. Sensitivity of new cell strain LPK to bovine viruses

New strain of bovine fetal lung LPK included in Cell Culture Collection VIEV. In the work reported here we examined sensitivity of cell culture LPK to bovine viruses. Our experiments demonstrated value LPK as model for experimental and diagnostic procedures. Key words: diploid strain, cell culture, cattle, viruses, sensitivity.

60        KorovinaD.G., VasilyevaS.A., SavchenkovaI.P.Formation of three-dimensional cellular constructions on the basis of bovine multipotent mesenchymal stem cells for assessment of the toxicity of volatile substances in vitro

The article discusses the findings as a result of experiments on using hanging drop technique for culturing bovine multipotent mesenchymal stem cells (ММSC) for assessment of the cellular toxicity of volatile substances. Key words: multipotent mesenchymal stem cells, bovine, three-dimensional cellular constructions, hanging drop technique, cytotoxicity, volatile substances.    

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CONTENTS №10-2014