CONTENTS №3-2016

INVASIVE DISEASES

28        Gluhareva E.V., Abramov V.E., Balyshev A.V., Kashkovskaya L.M. Cyflunit Flok – efficient means to combat wohlfahrtiosis in sheep

The article is devoted to combating infestations of sheep. It provides data on the use efficacy of the Cyflunit Flok drug in the treatment of sheep infected with wohlfahrtiosis. Particular attention is drawn to the therapeutic effect of the drug and the ease of its use. Key words: sheep, ectoparasites, myiasis, insecticides, wohlfahrtiosis, therapeutic efficacy, combating myiasis.

30        Masalkova Y.Y. The assessment of the destructive effects of chemical substances and preparations for eggs of dogs toxocara canis

There was tested in laboratory conditions the destructive action on T. canis eggs of some chemical agents (hydrogen peroxide, potassium permanganate, sodium hydroxide, lactic acid, sodium hypochlorite) and disinfectants (Biopag-D, Megadez, Ecosan, Belizna). It was established the high ovocide effect of 10 % aqueous solution of Megadez and Ecosan at the time of exposure of at least 24 hours at room temperature. The other tested preparates does not demonstrated sufficient desinvasion activity. Key words: desinvasion, ovocide activity, T. canis.

OBSTTETRICS, GYNECOLOGY

34        Narizhnyi A.G., Dzhamaldinov A.Ch. Technological parameters for improving reproductive function in replacement gilts

The main technological parameters for breeding and rearing of replacement gilts have been analyzed. The most favorable feeding strategy is adjusted; in addition, the replacement gilt body weight and age at the first insemination are determined. Key words: replacement gilts, feeding, weight, age, insemination effectiveness.

NONINFECTIOUS DISEASES

37        Terletskiy V.P., Dementieva N.V., Tyshchenko V.I., Mitrofanova O.V., Krutikova A.A., Zozulya O.K., Beishova I.S. Prevalence of lethal recessive mutations in breeding cattle of Leningrad region

Use of foreign genetic material in dairy breeding industry accounts not only for raise of milk productivity but also for spread of harmful recessive gene alleles which in homozygous state cause mortality of embryos and calves at early stages of development. Veterinary treatment to combat phenotypic consequences is not effective. Identification of these alleles give the possibility to stop their spread by elimination of animal-carriers from breeding programs. The frequency of harmful recessive mutations in the large breeding farms of Leningrad region was determined. Key words: alleles, breeding animals, recessive mutations.

42        Satyukova L.P., Krasnova I.A., Marisyuk A.R., Barashkov G.K. Macro- and microelements distribution in an organism of males of a guinea pig Cavia porcellus

Remarkable differences in the ratio of microelements (MEs) have been revealed by employment of the optical & mass-spectrometric atomic emission method in the analysis of content of 31 MEs in 20 different organs and tissues of male guinea pig C. porcellus. Apparently, these differences may cause drug diseases that depend on the functional groups characteristics in medicinal drugs. The metal-ligand homeostasis (MLH) of different organs and tissues is affected by them in different ways. They can act as epigenetic factors (EF) in the differentiation of blastomeres as well. Key words: micro- and macroelements distribution in an organism of males of a guinea, the metall-ligand homeostasis, the differentiation of cells in ontogenesis and histogenesis, atomic emission analysis method.

PHARMACOLOGY AND TOXICOLOGY

47        Cherednichenko Y.V., Semenov E.I., Matrosova L.E., Tremasov M.Ja., Zhestkov N.N. Efficiency of use sorbent Fitosorb at chronic poisoning of animals by tetramethylthiuramdisulfide

The result of in vitro studies the ability of drug Fitosorb to absorb the tetramethylthiuram and preventive efficiency this sorbent at chronic toxicity rats and sheep induced by this carbamate pesticide. Key words: sheep, intoxication, sorbent, white rat, tetramethylthiuram.

50        Moiseev A.N., Baryshnikov P.I. The biological role of interferon gamma in the regulation of immune animals

The article describes the characteristics of endogenous interferon gamma - regulatory cytokine immune response, its immunoregulatory role. Showing producers of gamma interferon, and target cells with which it interacts, and regulates their functional activity. Interferon gamma have antiviral, antibacterial, immunomodulatory and antiproliferative effects. Key words: immunity, cytokines, interferon gamma, recoferon gamma, immunomodulator, antiviral, blood cells.