CONTENTS №4-2016

3 Mischenko A.V., Karaulov A.K., Mischenko V.A. Routes of spread and mechanisms of transmission of lumpy skin disease virus

The information on routes of spread and mechanisms of transmission of lumpy skin disease virus is presented in the paper. The lumpy skin disease agent is a DNA-containing virus belonging to genus Capripoxvirus, family Poxviridae. Lumpy skin disease in cattle causes significant economic losses. Lumpy skin disease is a viral highly contagious emergent transboundary infection. The disease is characterized by lesions in skin, mucous membranes of respiratory and digestive systems, lymphatic system and parenchymatous organs. The agent is excreted with exhaled air, saliva, semen, milk, nasal and ocular excudates and it is also excreted by affected skin areas and mucous membranes. Skin, mucous membranes of respiratory and digestive tracts, conjunctiva are portals of infection. Key words: cattle, lumpy skin disease, Asiatic buffaloes, lesions in skin and mucous membranes, respiratory and digestive tracts, transboundary infection.

PRACTIC: EXPERIMENT, PROBLEMS, PERSPECTIVES

7 Donnik I.M., Voronin B.A. New veterinary legislation

The authors of paper analyze changes in the law "About veterinary" аnd presents own opinion on the further development of legal regulation in the field of veterinary activities and the full implementation of the law "About veterinary". Key words: legal regulation, legislation, veterinary.

10 Yunaev A.D. Оpportunities for the prevention and treatment of pigs with respiratory diseases

Respiratory diseases cause significant economic losses to swine farms. The article presents the characteristics of the most dangerous diseases of this group with a bacterial etiology, as well as describes the tools used for their prevention and treatment on swine complexes. Key words: antimicrobial agents, respiratory disease, swine, Actinobacillus pleuropneumoniae, Haemophilus parasuis, Mycoplasma hyopneumoniae.

13 Manin T.B., Маximov Т.P., Teimurazov M.G., Platonov М.Е. The new data of spread of infectious coryza in Russia and some CIS countries in 2013 – 2015 years

The article consists from actual information about distribution of Avibacterium paragallinarum on the territories of Russian Federation, Ukraine, Kazakhstan and Belarus in 2013 – 2015 years. Key worlds: Infectious Coryza, Avibacterium paragallinarum, Haemophilus paragallinarum, distribution.

INFECTIOUS DISEASES

17 Glotov A.G., Glotova T.I., Semenova O.V., Koteneva S.V. Detection of viral diarrhoea virus genome in cattle with reproduction pathology

The data for the study of serological status to BVD virus in cattle and frequency of detection of the viral genome by RT-PCR in the big dairy farms are submitted. Heifers after artificial insemination and heifers especially after abortion, revealed high titers of specific antibodies to the virus. Up to 71,4 % of heifers responded 64 – 128-fold seroconversion to the pathogen through 1 – 3 months after artificial insemination in cows the figure was 36,50 %. High levels of antibodies in heifers can serve as a criterion for the birth of persistently infected calves and further development of fertility and gynecological pathology in breeding stock. The number of virus carriers among the heifers was 10,6 %, dry heifers 8,83 %, while the calves are born to 5,50 %, higher than the corresponding figures of cows second and third lactation. The virus genome was detected in most organs of aborted fetuses from heifers in step 4 – 6 months (40,0 %), 6 – 9 months (24,0 %) stillbirth calves (29,23 %). In cows, the figures were 17,54; 10,34 and 20,51 % respectively. The presence of the virus in vaginal and uterine secretions was of "transition" nature and amounted to 28,98 and 13,50 %, respectively. The real value in the pathology of the reproduction system of the virus can "masked" by other agents of viral and bacterial origin. In order to establish its role in the pathology of reproduction is necessary to conduct complex of diagnostic tests (serological and molecular) in the most susceptible to infection with animal groups. Il. 3. Ref. 18. Key words: cattle, reproduction pathology, viral diarrhea-mucosal disease, virus, genome, PCR, serological investigations, molecular investigations.

23 Timoshina S.V., Badeeva O.B. Еconomic damage of enzootic bovine leukemia

The authors' analysis demonstrate that keeping of a BLV-seropositive cows in farms of Volgograd region entails with significant economic losses due to a decrease in milk production on an average of 12,7 % and milk fat on 0,09 %. Key words: bovine enzootic leukemia, cow, fat content of milk, recovery, milk production.

25 Gulukin M.I., Sotnikov A.N., Luchko M.A., Stafford V.V. Volodko D.V. Clinical and laboratory diagnosis contagious diseases of the brood of bees

The article describes a comprehensive diagnosis of contagious diseases of the brood of bees. Key words: clinical signs, laboratory diagnosis, death of the brood, American foulbrood, European foulbrood, sack-brood, ascosphaerosis, aspergillosis, varroosis.

INVASIVE DISEASES

28 Kuchboev A.E., Amirov O.O., Shakarboev E.B., Karimova R.R., Golovanov V.I., Abramatov M.B., Kuznetsov D.N. The epizootology of parabronemosis of domestic ruminants in Uzbekistan

According to the results of helminthological autopsies of 275 cattle and 611 small cattle (sheep and goats) in desert and semi-desert areas of Uzbekistan it was found that the extensity of infection by Parabronema skrjabini (Nematoda: Spirurata) was 37,1 % in cattle and 44,0 % in small cattle. 1737 specimens of Diptera, including Lyperosia titilans, Lyperosia irritans, Stomoxys calcitrans, Musca corvina, Musca domestica and several species of Tabanidae were studied as putative intermediate hosts of P. skrjabini. The larvae of P. skrjabini were found in L. titilans, L. irritans and S. calcitrans. Key words: cattle,smallcattle, Parabronema skrjabini, Uzbekistan.

Reported methods for canine estrus induction include the use of synthetic estrogens, exogenous gonadotropins (PMSG, LH, FSH, hCG, human menopausal gonadotropin), GnRH agonists (lutrelin, buserelin, leuprolide, deslorelin), dopamine agonists (bromocryptine and cabergoline). The applicability of some of these methods for clinical practice is questionable. GnRH agonist deslorelin and dopamine agonists seem to be encouraging schemes in dogs. Key words: bitch, estrus induction, estrogens, gonadotropins, dopamine agonists, bromocryptine, cabergoline, GnRH agonists, deslorelin.

Systematic disinfection of livestock buildings for cattle is the key to successful prevention of different etiology diseases. The implementation of anti-epizootic measures at 90% will ensure the safety of livestock and economic well-being of the economy. Disinfection with modern precompositional drug VIROCID ensures the Biosafety of the enterprise. Veterinarian of the dairy farming enterprise, using CID LINES products, gave an interview about the sanitary activities through drug VIROCID. Keywords: prevention, cost of treatment, pathogenic microorganisms, disinfection, biosecurity, dairy farming.

39 Tyurin V.G., Potemkina N.N., Kamalov R.A. Dynamics of release of formaldehyde from fiberglass on the basis of epoxy and dianovy pitch in air

In this article dynamics of release of formaldehyde from fiberglass on the basis of an epoxy dianovy of pitch is presented to air. Key words: formaldehyde, fiberglass, air, migration, livestock room.

42 Semenenko M.P., Kuzminova E.V., Onischuk F.D., Tyapkina E.V. Etiopathogenesis and features of hepatotropic therapy hepatoses of highly productive dairy cattle

There are considered etiological factors and pathogenetic mechanisms of hepatoses of highly productive dairy cattle and methods of their pharmacotherapy. The features of the application hepatoprotectors to ruminants are described. Key words: cattle, hepatoprotectors, hepatose, therapy.

46 Borisov M.S., Mochalina O.S., Hohlova N.S. Serous synovitis and tendovaginitis in animals

There is present the information about etiology, pathogenesis, clinical signs, diagnosis and treatment of serous synovitis and tendovaginitis in animals. Key words: diagnosis, cattle, treatment, synovitis, dogs, tendovaginitis.

50 Garbuzov A.V. Improving the efficiency of quality assurance of medicines for veterinary use

The analysis of the status of conformity assessment of medicinal products for veterinary use, recommendations to improve the effectiveness of the quality assurance systems for medicines. Keywords: veterinary preparation, quality.

52 Jacques J., Manukyan V.A., Tashbulatov A.A., Tretyakov S.V. Effective method of increasing productivity of birds’ parent stock at the latter half of productivity period

With the purpose to increase birds’ productivity and to low the level of oxidative stress, the French company Qalian has been developed a nutritional additive. A tablet Acti’z Anti Ox composites a complex of 4 plants which has a proven antioxidant action, and selenium in water-soluble form. Acti’z Anti Ox improves zoo technical parameters at the latter half of productivity period of breeders (hens, partridges and ducks). It can be recommended for all birds’ species in order to increase performance and profits of manufacturers of incubative or marketable eggs and poultry. Keywords: productivity period, breeders, laying hens, eggs.

56 Sanin A.V., Pronin A.V., Narovlyansky A.N., Deyeva A.V., Kozhevnikova T.N., Sanina V.Yu., Timofeeva T.Yu., Annikov V.V., Kudinov A.V., Annikova L.V., Larina E.К. Gamavit stimulates somatotropic hormone production and weight gain in suckling piglets

Previously it was shown that Gamavit induced 2-fold increase in the somatotropic hormone (STH) blood levelincalves and lambs. Here we studied Gamavit effect on the STH blood level in suckling piglets. Using method of enzyme immunoassay we shown that during the study level of STH in the experimental group gradually increased from 8,5mIU/ l before the experiment to 14,3 mIU/l on the 5th day. In the control group it ranged from 7,5mIU/l to 10,2 mIU/l. At the end of the experiment greatest body weight gain was observed in the experimental group and amounted 45,450 g compared with 26,700 g in the control group piglets. Key words: Gamavit, somatotropic hormone, suckling piglets, pig-breeding.

There were selected the optimal methods of H1 hemagglutinin purification and concentration from influenza A virus strain А/duck/Alberta/35/76 (Н₁N₁). The optimal schemes of preparing active and specific antisera for this subtype of influenza A virus were developed. The prepared antisera are suitable for detection and identification of it hemagglutinin and for determination of immunity stress by hemagglutination inhibition reaction and solid-phase enzyme-linked immunosorbent assay. Key words: antiserum, influenza A virus, hemagglutinin, enzyme-linked immunosorbent assay, hemagglutination test, hemagglutination inhibition test.